Dry the skin well before applying the cream.

Use a diaper rash cream especially if you are using diapers for long hours. It acts as a barrier between the diaper and the baby's skin. Most importantly apply in the folds of the skin, the sides of the legs, the rectal area. If it is a baby boy then under the scrotum and penis as well Then you can apply a thin layer on the rest of the bottom as well. Any cream which suits the baby's skin is considered fine.